Why Do I Get Cold Sores When I'm Sick?

Published: 2023-11-27

Updated: 2024-05-15

Ever wonder why those pesky cold sores decide to make an appearance when you're feeling under the weather? Cold sores – also known as fever blisters – are pretty common, especially when you're dealing with an illness. Let's find out where these annoyances come from and how to deal with them. 

Combat herpes and cold sores with confidence.

Explore our tailored valacyclovir treatments designed for men.

Get Started

Understanding Cold Sores

Cold sores are caused by the herpes simplex virus (HSV). There are two types of herpes simplex viruses: HSV-1 and HSV-2. Cold sores are primarily associated with HSV-1, although HSV-2 can also cause them. These viruses are highly contagious and can be transmitted through direct contact with an infected person or their saliva. Once infected, the virus can remain dormant in the body and reactivate, leading to the development of cold sores.

Connection Between Cold Sores and Illness

The link between cold sores and illness – particularly respiratory infections like the common cold – lies in the body's immune response. When you’re sick, your immune system is often weakened as it fights off the invading pathogens. This weakened immune system creates an opportunity for the dormant herpes simplex virus to reactivate and cause cold sores.

Stress as a Trigger

While illness can certainly play a role in triggering cold sores, stress is another significant factor. Stress weakens the immune system and can also directly activate the herpes simplex virus. Therefore, individuals who are both sick and stressed may be more prone to developing cold sores.

The Role of Fever in Cold Sores

The term "fever blister" suggests a connection between cold sores and elevated body temperature. And it is true that a fever can be a trigger for cold sores. 

When the body experiences a fever, it is a sign that the immune system is actively responding to an infection. The stress on the body during a fever can stimulate the reactivation of the herpes simplex virus, leading to the development of cold sores.

Cold Sores and Colds – Are They Directly Linked?

While there is a correlation between being sick and developing cold sores, it's essential to clarify that cold sores are not directly caused by the common cold virus. The common cold is typically caused by rhinoviruses and other respiratory viruses, whereas cold sores are specifically associated with the herpes simplex virus. 

However, the weakened immune system during a cold can create conditions favorable for the reactivation of the herpes simplex virus, contributing to the occurrence of cold sores.

Preventing Cold Sores During Illness

Given the connection between illness and cold sores, it becomes crucial to take preventive measures during times of sickness. Maintaining good hygiene practices, such as frequent handwashing, can reduce the risk of spreading the virus. Additionally, managing stress levels and ensuring adequate rest during illness can help support the immune system and minimize the likelihood of cold sore outbreaks.

Lifestyle Factors and Recurrence

Understanding the triggers of cold sores extends beyond illness and stress. Lifestyle factors such as exposure to sunlight, hormonal changes, and dietary choices can also influence the recurrence of cold sores. Identifying and managing these triggers can be instrumental in preventing future outbreaks.

Treatment and Management

When you're sick, the last thing you want to deal with is a cold sore on your mouth. Fortunately, Rex MD can help you treat them. With antiviral medications like valacyclovir, your outbreak can be managed quickly and easily. And, with fast and discreet delivery, you won't even have to leave your home. Get started today with a free online consultation about your symptoms.