What is Enclomiphene?

March 26, 2024

4 mins

Enclomiphene (or enclomiphene citrate) is a non-steroidal selective estrogen receptor modulator (SERM) used to treat symptoms of hypogonadism in men.

The oral medication is often prescribed as an alternative to testosterone replacement therapy, as its mechanism differs from the drugs used in TRT.

Enclomiphene is typically associated with Clomid (clomiphene citrate) – a SERM made up of enclomiphene and another isomer zuclomiphene.

While enclomiphene and Clomid are both SERMs, there are some key differences in their chemical composition, potency, and specific applications.

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What Does Enclomiphene Do?

As a SERM, enclomiphene stimulates the body’s natural testosterone production. By increasing testosterone levels, enclomiphene may help improve symptoms such as low libido, fatigue, and reduced muscle mass, promoting overall well-being and vitality in men.

This is different from other TRT treatments that typically involve directly administering external testosterone through supplementation to replace the body’s natural testosterone levels.

How Does Enclomiphene Work?

Enclomiphene works by stimulating the release of hormones that are needed for testosterone production in the testes and blocking the negative feedback of estrogen in the hypothalamus and pituitary gland.

By blocking estrogen receptors, enclomiphene prevents this negative feedback mechanism and allows for increased production of FSH and LH. This leads to stimulation of the testes to produce more testosterone, ultimately improving sperm production and fertility in men with low testosterone levels.

Is Enclomiphene a Steroid?

No, enclomiphene is not a steroid – it’s a non-steroidal selective estrogen receptor modulator.

SERMS are non-steroidal which means that they stimulate the body's natural testosterone production process. Steroids directly provide the body with synthetic testosterone, instead of enhancing the body's own production of this hormone.

Enclomiphene can potentially offer a safer and more balanced way to improve testosterone levels without disrupting natural hormone production or causing unwanted side effects compared to steroids.

The choice between a SERM and synthetic testosterone may impact overall hormonal regulation and safety considerations, so it’s important to consider your health needs and goals when selecting a treatment approach.

Who Should Use Enclomiphene?

Enclomiphene is typically used to treat symptoms of hypogonadism in men. Hypogonadism is a condition in which the body does not produce enough testosterone, leading to symptoms such as low libido, fatigue, decreased muscle mass, and mood changes.

Men who have been diagnosed with hypogonadism and have low testosterone levels may benefit from enclomiphene therapy to help stimulate their body's natural testosterone production process.

How Should You Take Enclomiphene?

Taking enclomiphene between 7:00 a.m. and 10:00 a.m. or splitting the dose into two daily administrations is recommended by some health experts. Testosterone levels peak during this time frame, so taking enclomiphene between these hours may optimize the medication's efficacy in addressing testosterone-related issues.

Be sure to follow your healthcare provider’s dosage recommendations and schedule exactly for best results and to minimize the chance of side effects.

How Much Does Enclomiphene Cost?

The price of enclomiphene can vary significantly depending on variables like location, formulation type (generic or brand name), and insurance status. Uninsured individuals may expect to pay anywhere from around $50 to $150 or higher for a monthly supply of enclomiphene tablets.

Do You Need a Prescription for Enclomiphene?

Yes, enclomiphene is a prescription medication, and you would need a prescription from a licensed healthcare provider to obtain and use it.

Enclomiphene is used to treat symptoms of hypogonadism in men, and a healthcare provider will need to evaluate your condition, conduct necessary tests, and determine if enclomiphene is an appropriate treatment option for you before prescribing it.

How Can Rex MD Help?

Balanced testosterone levels are a key factor in men’s health, and fortunately, Rex MD has got what you need to boost your testosterone.

With the Rex MD TestoRx program , you’ll have access to testosterone-boosting medications like Clomid that will help you feel like yourself again.

To find out if the program is right for you, just answer a few questions about your symptoms and medical history. Then, you’ll be able to schedule a virtual call with the Rex MD care team.

Your provider will order lab work for you and determine if you’re eligible for Clomid or another treatment option based on your testosterone levels.

Get started today.