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  • NAD+ helps boost energy, mood, mental
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  • Supports healthy metabolism, longevity
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  • Helps you age vibrantly, supports DNA
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NAD+ (Nicotinamide Adenine Dinucleotide) helps counter age-related decline in a coenzyme, essential for metabolism, DNA repair, and overall cellular health.

Important safety information

NAD+ (Nicotinamide Adenine Dinucleotide) helps counter age-related decline in a coenzyme, essential for metabolism, DNA repair, and overall cellular health.

Important safety information
Injection Treatment

NAD+ helps men & women age with confidence.

As we age, stress and lifestyle choices accelerate the natural decline of NAD+ levels. Restoring NAD+ powers essential cellular processes that keep our muscles, brain, and immune system functioning strong and balanced.

NAD+ recharges mitochondria, also known as the "body’s cellular batteries”, to sustain energy, resilience, and long-term wellness.

  • NAD+ helps sustain long-term wellness
  • Replenishes enzyme that declines with age
  • Fuels metabolism and cellular resilience
Important Safety Information

NAD+ is essential to cellular health.

NAD+ (nicotinamide adenine dinucleotide) is an essential coenzyme present in every cell of the body. It supports critical functions such as energy metabolism and enzymatic activity.+

Since NAD+ levels naturally decrease with age, many patients consider therapy through RexMD as part of their wellness plan.

Boosting NAD+ helps support cellular energy production, which may improve overall performance and daily function. Research has linked NAD+ to benefits such as better mobility, reduced inflammation, and improved quality of life.

Because NAD+ also plays a role in neurotransmitter production and cell signaling in the brain, it may promote mental clarity and focus.

Science-backed treatment 100% from home.

Get NAD+ prescribed online and delivered from a US-state licensed pharmacy, right to your door when you need it. Your health and well-being is our absolute top priority.

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Compounded treatment††
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Risk and Safety Disclosures

NAD+

Adverse Reactions

- Flushing, warm sensation
- Headache, dizziness, spanghtheadedness
- Nausea, abdominal cramping

Contraindications & Precautions

- Known hypersensitivity to NAD+ or any component of the solution
- Active infection or inflammation

Precautions

- Patients should be monitored during and after administration for tolerance

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Important Safety Information

NAD+
Last Updated: Oct 6, 2025
 

Description
Nicotinamide Adenine Dinucleotide (NAD⁺) is crucial for metabolic activity (needed in over 500 enzymatic processes) in the body and in maintaining health. NAD+ is critical in energy metabolism, homeostasis in mitochondria and in cellular survival or death. In addition, NAD+ is a mediator of cellular functions including maintenance and repair of DNA. As people age, NAD+ levels decrease. Restoring NAD+ levels can improve altered metabolism, decrease disease susceptibility, and promote longevity.1-6

The potential benefits of increasing NAD+ levels include:

  • Improved brain functioning
  • Brain protection from neurodegeneration
  • Improved blood vessel vascularization
  • Reduced hepatic steatosis
  • Improved muscle strength and pancreas functioning (increased insulin secretion)
  • Reduced inflammation

Mechanism of Action
NAD+ is critical for metabolism and physiological function. It accepts electrons during metabolic reactions to become NADH (reduced form). NADH uses the electron to donate to other molecules. This is important for ATP production in the body. This process occurs during glycolysis, fatty acid oxidation, and the TCA cycle. There is a continuous conversion of NAD+ to NADH in cells in the body which is critical for energy flow. NAD+ is also important for sirtuin regulation (DNA repair, inflammation processes, and fat metabolism). It is a substrate for PARPs (poly (ADP-ribose) polymerases) (repair of damaged DNA), and is important to prevent neurodegenerative processes.1-6

Adverse Reactions
Common2-6

  • Flushing, warm sensation
  • Headache, dizziness, lightheadedness
  • Nausea, abdominal cramping

Contraindications & Precautions
Contraindications2,6

  • Known hypersensitivity to NAD+ or any component of the solution
  • Active infection or inflammation

Precautions2,6

  • Patients should be monitored during and after administration for tolerance

Storage
Store at 2°C to 8°C (36°F to 46°F); Protect from light, heat, and moisture.

References

  1. https://www.nad.com/what-is-nad
  2. Hwang ES, Song SB. Possible Adverse Effects of High-Dose Nicotinamide: Mechanisms and Safety Assessment. Biomolecules. 2020 Apr 29;10(5):687.
  3. Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during aging. Nat Rev Mol Cell Biol. 2021 Feb;22(2):119-141.
  4. Xie N, Zhang L, Gao W, Huang C, Huber PE, Zhou X, Li C, Shen G, Zou B. NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential. Signal Transduct Target Ther. 2020 Oct 7;5(1):227.
  5. Mark, J. The Vital Role of NAD in Cellular Metabolism and Aging https://www.therealgutdoctor.com/the-vital-role-of-nad-in-cellular-metabolism-and-aging/. August 13, 2024. Accessed June 29, 2025
  6. Lopez J NAD IV Therapy Side Effects: Exploring the Potential Risks. https://www.azivmedics.com/side-effects-of-nad-therapy July 6, 2023. Accessed June 30, 2025.

Disclaimer
This information is for educational purposes only. This compounded product has not been reviewed, approved, or evaluated by the Food and Drug Administration for safety and effectiveness. This product is not intended to diagnose, treat, cure, or prevent any disease. No claims are made regarding treatment, cure, or prevention of any disease or condition.

This information may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects.